Yes, Artisan HD can take your images and create digital photos on acrylic. There are two options when it comes to printing on acrylic: direct to substrate or surface mounted. 
When your image is printed direct to the substrate surface, such as acrylic or a board, the uv-cured ink bonds to the surface. When it is surface mounted, the image is printed on HD photo paper, then mounted to the acrylic. This is also referred to as second surface or face mounting. Both processes create stunning, professional ways to print digital photos on acrylic.
To see more about the process, read more HERE.